Faculty Member

Martin Zack Ph.D., Psychology

Email Address(es)
Office Phone
(416) 535-8501, ext. 6052
Office Address
Neuroscience Dept/Centre for Addiction and Mental Health 33 Russell Street Toronto, ON M5S 2S1
Clinical Public Health Division
Adjunct Professor
SGS Status
Associate Member
Appointment Status
Status Only

Research Interests

  • Biobehavioural Aspects of Problem Gambling
  • Relapse in Alcohol Use and Gambling Disorders
  • Concurrent Anxiety and Alcohol Use Disorders

Primary Teaching Responsibilities

  • ATS 3700: Behavioural effects of alcohol and drugs

Current Research Projects

  • 2005-present: Effects of stress and alcohol cues on implicit alcohol cognitions and inhibitory control in problem drinkers
  • 2008-present: Positron emission tomography (PET) assessment of brain dopamine function in pathological gamblers and healthy controls
  • 2005-8: Effects of gender and drink-stress sequence on alcohol-stress response dampening in young, high and low anxiety sensitive drinkers
  • 2005-7: Effects of dopamine D2 receptor blockade on responses to slot machine gambling in pathological gamblers and healthy controls
  • 2008-10: Medication effects in problem gamblers with high vs. low impulsivity
  • 2008-10: The role of uncertainty in vulnerability to problem gambling and substance addiction

Representative Publications

Tremblay, A.M., Desmond, R. C., Poulos, C. X., & Zack, M. (in press). Haloperidol modifies instrumental aspects of slot machine gambling in pathological gamblers and healthy controls. Addiction Biology.

Zack, M., & Poulos, C.X. (2009). Parallel roles for dopamine in pathological gambling and psychostimulant addiction.  Current Drug Abuse Reviews, 2, 11-25.
Zack, M., & Poulos, C.X. (2008). Effects of the atypical stimulant modafinil on a brief gambling episode in pathological gamblers with high versus low impulsivity. Journal of Psychopharmacology Jun 26. [Epub ahead of print]
Stewart, S. H., & Zack, M. (2008). Development and psychometric evaluation of a three-dimensional Gambling Motives Questionnaire. Addiction, 103, 1110-1117.

Zack, M., & Poulos, C. X., Aramakis, V. B., Khamba, B. K., & MacLeod, C. M. (2007). Effects of drink-stress sequence and gender on alcohol stress response dampening in high and low anxiety sensitive drinkers. Alcoholism: Clinical and Experimental Research. 31, 411-422
Zack, M., & Poulos, C. X. (2007). A D2 antagonist enhances the rewarding and priming effects of a gambling episode in pathological gamblers. Neuropsychopharmacology 32, 1678-1686.