Faculty Member

Malcolm Koo Ph.D.

Email Address(es)
m.koo@utoronto.ca
Office Phone
+886 5 264 8000 ext 3211
Office Address
Department of Medical Research Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation Dalin, Chiayi, Taiwan 62247
Division(s)/Office
Social & Behavioural Health Sciences Division
Position
Adjunct Professor

Research Interests

  • Secondary data analysis
  • Complementary and Alternative Medicine
  • Health Survey
  • Ankylosing spondylitis

Education & Training History

  • Doctor of Philosophy, Epidemiology, Department of Public Health Sciences, University of Toronto, Canada, 2000.
  • Master of Science, Nutritional Sciences, University of Toronto, Canada, 1990.
  • Bachelor of Science, Nutritional Sciences, University of Toronto, Canada, 1987.

Primary Teaching Responsibilities

Professional Summary & Appointments

  • Adjunct Professor: Dalla Lana School of Public Health, University of Toronto (08/2005 – present)
  • Research Fellow: Department of Medical Research, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taiwan (11/2012-present)
  • Director and Associate Professor: Graduate Institute of Natural Healing Sciences, Nanhua University, Taiwan (8/2005 – 8/2010)
  • Chair and Associate Professor: Department of Natural Biotechnology, Nanhua University, Taiwan (08/2006 – 07/2008)
  • Assistant Professor: Department of Public Health Sciences, University of Toronto (09/2001 – 06/2005)

Honours & Awards

Current Research Projects

  • Secondary data analysis of the Taiwan’s National Health Insurance Research Database

Representative Publications (2013-present)

  1. Lin TK, Tu YR, Chen CW, Lin CL, Lin MN, Koo M*, CY Weng* (2018) Blood pressure reactivity and recovery to anger recall in hypertensive patients with type D personality. Acta Cardiologica Sinica (Koo & Weng are co-corresponding authors) (Accepted)
  2. Kao YH, Liu YT, Koo M*, Chiang JK* (2018) Factors associated with emergency services use in Taiwanese advanced cancer patients receiving palliative home care services during out-of-hours periods: A retrospective medical record study. BMC Palliative Care 17(1):46.
  3. Leung FW*, Koo M, Cadoni S, Falt P, Hsieh YH, Amato A, Erriu M, Fojtik P, Gallittu P, Hu CT, Leung JW, Liggi M, Paggi S, Radaelli F, Rondonotti E, Smajstrla Vit, Tseng CW, Urban O (2018) Water exchange produces significantly higher adenoma detection rate than water immersion – pooled data from two multi-site randomized controlled trials. Journal of Clinical Gastroenterology (Accepted)
  4. Cadoni S*, Liggi M, Gallittu P, Mura D, Fuccio L, Koo M, Ishaq S (2018) Underwater endoscopic colorectal polyp resection: feasibility in everyday clinical practice. United European Gastroenterology Journal 6(3):454–462. doi:10.1177/2050640617733923
  5. Koo M, Chen YW* (2017) An exploratory study of diabetes treatment articles on content farm websites. (in Chinese) Bulletin of the Taiwanese Association of Diabetes Educators 13(4):40–46.
  6. Lu MC, Koo M*, Lai NS* (2017) Incident spine surgery in patients with ankylosing spondylitis: a secondary cohort analysis of a nationwide, population-based health claims database. Arthritis Care & Research doi:10.1002/acr.23478. (Koo & Lai are co-corresponding authors)
  7. Lu MC, Tung CH, Wang CL, Huang KY, Koo M*, Lai NS* (2017) Incident osteoarthritis and osteoarthritis-related joint replacement surgery in patients with ankylosing spondylitis: a secondary cohort analysis of a nationwide, population-based health claims database. PLoS One 12(11):e0187594. doi:10.1371/journal.pone.0187594. (Koo & Lai are co-corresponding authors)
  8. Huang YS, Koo M, Chen JC, Hwang JH*. The association between tinnitus and the risk of ischemic cerebrovascular disease in young and middle-aged patients: A secondary case-control analysis of a nationwide, population-based health claims database. PLoS One 12(11):e0187474. doi:10.1371/journal.pone.0187474. (Koo & Huang contributed equally to this work)
  9. Tsai KW, Lin SC, Koo M* (2017) Correlates of depressive symptoms in late middle-aged Taiwanese women: Findings from the 2009 Taiwan National Health Interview Survey. BMC Women’s Health 17(1):103. doi:10.1186/s12905-017-0461-4
  10. Chen JC, Koo M, Hwang JH* (2017) Tinnitus is associated with a higher risk of benign brain tumors: A nationwide, population-based secondary cohort study of young and middle-aged adults. Neuroepidemiology 49(3–4):174–178. doi:10.1159/000481991 (Chen & Koo contributed equally to this work)
  11. Lu MC, Hsu H, Lin CH, Koo M* (2017) Systemic vasculitis is associated with a higher risk of lower extremity amputation in patients with severe peripheral arterial occlusive disease: a secondary analysis of a nationwide, population-based health claims database. Rheumatology International 37(11):1847–1852. doi:10.1007/s00296-017-3828-9
  12. Koo M, Lu MC* (2017) Preparing manuscripts for academic journals from the perspective of peer reviewers.  (in Chinese) Formosan Journal of Medicine 21(6):635–641. doi:6320/FJM.201711_21(6).0011
  13. Tseng CW, Koo M, Hsieh YH* (2017) Cecal intubation time between cap-assisted water exchange and water exchange colonoscopy: A randomized controlled trial. European Journal of Gastroenterology & Hepatology 29(11):1296–1302. doi:10.1097/MEG.0000000000000954
  14. Chiang JK, Lin CW, Wang CL, Koo M*, Kao YH* (2017) Cancer studies based on secondary data analysis of the Taiwan’s National Health Insurance Research Database: A computational text analysis and visualization study. Medicine 94(17):e6704. doi:10.1097/MD.0000000000006704 (Koo & Kao are co-corresponding authors)
  15. Lai NS, Wang CL, Lu MC, Koo M* (2017) Cardiovascular comorbidities of rheumatoid arthritis in Taiwanese adults: a retrospective single center study. Tzu Chi Medical Journal 29(3):171–173. doi:10.4103/tcmj.tcmj_62_17.
  16. Lin HL, Lin MH, Ho CC, Fu CH, Koo M* (2017) Psychometric properties of the Chinese version of the attitudes towards cardiopulmonary resuscitation with defibrillation (ACPRD-C) among female hospital nurses in Taiwan. International Emergency Nursing 33:7–13. doi:10.1016/j.ienj.2017.02.002
  17. Chen KC, Weng CY, Hsiao S, Tsao WL, Koo M* (2017) Cognitive decline and slower reaction time in elderly individuals with mild cognitive impairment. Psychogeriatrics 17(6):364–370. doi:10.1111/psyg.12247
  18. Lu MC, Hsu BB, Koo M*, Lai NS* (2017) Higher risk of incident ankylosing spondylitis in patients with uveitis: a secondary cohort analysis of a nationwide, population-based health claims database. Scandinavian Journal of Rheumatology 46(6):468–473. doi:10.1080/03009742.2017.1282686 (Koo & Lai are co-corresponding authors)
  19. Koo M, Peng CN, Lin SC* (2017) Analysis of the visibility and content of nursing on hospital websites in Taiwan.  (in Chinese) Cheng Ching Medical Journal 13(3):50–57.
  20. Koo M* (2017) Twenty years of clinical trials on aromatherapy research: a bibliometric analysis. Evidence-Based Natural Medicine 2(1):27–58.
  21. Koo M* (2017) A bibliometric analysis of two decades of aromatherapy research. BMC Research Notes 10(1):46. doi:10.1186/s13104-016-2371-1.
  22. Koo M, Tsai KW, Lin SC* (2017) Health effects of fine particulate matter exposure.  (in Chinese) Journal of Medicine and Health 6(1):13–22.
  23. Chen CM, Chen CY, Chen HY, Koo M* (2017) Knowledge of cold syrup and the five core competencies of medication use.  (in Chinese) Journal of Medicine and Health 6(1):61–73.
  24. Wu LF, Yang SH, Koo M* (2017) Psychometric properties of the Chinese version of Spiritual Index of Well-Being in elderly Taiwanese. BMC Geriatrics 17(1):3. doi:10.1186/s12877-016-0392-1
  25. Lai NS, Koo M, Yu CL, Lu MC* (2017) Immunopathogenesis of systemic lupus erythematosus and rheumatoid arthritis: the role of aberrant expression of non-coding RNAs in T cells. Clinical and Experimental Immunology 187(3):327–336. doi:10.1111/cei.12903 (Koo & Lai contributed equally to this work)
  26. Cadoni S, Falt P, Rondonotti E, Radaelli F, Fojtik P, Gallittu P, Liggi M, Amato A, Paggi S, Smajstrla V, Urban O, Erriu M, Koo M, Leung FW* (2017) Water exchange for screening colonoscopy increases adenoma detection rate: a multicenter, double-blinded randomized controlled trial. Endoscopy 49(5):456–467. doi:10.1055/s-0043-101229
  27. Chuang MH, Chuang TL, Koo M, Wang YF* (2017) Trabecular bone score (TBS) reflects trabecular microarchitecture deterioration and fragility fracture in female adult patients receiving glucocorticoid therapy: A pre-post controlled study. BioMed Research International 2017:4210217. doi:10.1155/2017/4210217
  28. Chang JH, Koo M, Wu SW, Chen CY* (2017) Effects of a 12-week program of Tai Chi exercise on the kidney disease quality of life and physical functioning of patients with end-stage renal disease on hemodialysis. Complementary Therapies in Medicine 30:79–83. doi:10.1016/j.ctim.2016.12.002 (Koo & Chang contributed equally to this work)
  29. Hsieh YH*, Tseng CW, Hu CT, Koo M, Leung F (2017) Prospective multicenter randomized controlled trial comparing adenoma detection rate in colonoscopy using water exchange, water immersion and air insufflation. Gastrointestinal Endoscopy 86(1):192–201. doi:10.1016/j.gie.2016.12.005
  30. Lu MC, Juan CY, Koo M*, Lai NS* (2017) Higher incidence of psychiatrist-diagnosed depression in Taiwanese female school-age children and adolescents with type 1 diabetes: a nationwide, population-based retrospective cohort study. Journal of Child and Adolescent Psychopharmacology 27(3):281–284. doi:10.1089/cap.2016.0004 (Koo & Lai are co-corresponding authors)
  31. Hung YT, Lay CJ, Wang CL, Koo M* (2017) Characteristics of nontyphoidal Salmonella gastroenteritis in Taiwanese children: A 9-year period retrospective medical record review. Journal of Infection and Public Health 10(5):518–521. doi:10.1016/j.jiph.2016.09.018
  32. Koo M, Hwang JH* (2017) Risk of tinnitus in patients with sleep apnea: A nationwide, population-based case-control study. Laryngoscope 127(9):2171–2175. doi:10.1002/lary.26323
  33. Koo M, Tsai KW, Lin SC* (2016) Prevention and care of heat emergencies in the elderly.  (in Chinese) Taiwan Geriatrics and Gerontology 11(4):225–236.
  34. Yang CC, Chen CY, Wu CC, Koo M*, Yu ZR, Wang BJ* (2016) Panax ginseng fraction F3 extracted by supercritical carbon dioxide protects against oxidative stress in ARPE-19 cells. International Journal of Molecular Sciences 17(10):1717. doi:10.3390/ijms17101717 (Koo & Wang are co-corresponding authors)
  35. Koo M, Chen JC, Hwang JH* (2016) Risk of peripheral artery occlusive disease in patients with vertigo, tinnitus, or sudden deafness: a secondary case-control analysis of a nationwide, population-based health claims database. PLoS ONE 11(9):e0162629. doi:10.1371/journal.pone.0162629 (Koo & Chen contributed equally to this work)
  36. Yu HC, Lai PH, Lai NS, Huang HB, Koo M, Lu MC* (2016) Increased serum levels of anti-carbamylated 78-kDa glucose-regulated protein antibody in patients with rheumatoid arthritis. International Journal of Molecular Sciences 17:1510. doi:10.3390/ijms17091510
  37. Koo M, Tung CH, Peng CN* (2016) Nursing care management of patients with juvenile idiopathic arthritis. (in Chinese) Journal of Mackay Nursing 10(2):7–15.
  38. Koo M, Lu MC, Lin SC* (2016) Predictors of Internet use for health information among male and female Internet users: Findings from the 2009 Taiwan National Health Interview Survey. International Journal of Medical Informatics 94:155–1 doi:10.1016/j.ijmedinf.2016.07.011 (Koo & Lu contributed equally to this work)
  39. Koo M, Kuo MH* (2016) The opportunities for editing pharmacology articles in Chinese Wikipedia.  (in Chinese) Journal of the Taiwan Pharmacy 32(3):35–39.
  40. Chen PH, Weng YM, Yu ZR, Koo M, Wang BJ* (2016) Extraction temperature affects the activities of antioxidation, carbohydrate-digestion enzymes, and angiotensin-converting enzyme of Pleurotus citrinopileatus Journal of Food and Drug Analysis 24(3):548–555. doi:10.1016/j.jfda.2016.02.005
  41. Lu MC, Chang SC, Huang KY, Koo M*, Lai NS* (2016) Higher risk of thyroid disorders in young patients with type 1 diabetes: A 12-year nationwide, population-based, retrospective cohort study. PLOS ONE 11(3):e0152168. doi:10.1371/journal.pone.0152168 (Koo & Lai are co-corresponding authors)
  42. Koo M, Lai CY* (2016) The pitfalls of academic publishing: predatory journals (in Chinese) Formosan Journal of Medicine 20(2):216–221.
  43. Chien YS, Yu ZR, Koo M*, Wang BJ* (2016) Supercritical fluid extractive fractionation – study of the antioxidant activities of Panax ginseng. Separation Science and Technology 51(6):954–960. doi:10.1080/01496395.2016.1140202 (Koo & Wang are co-corresponding authors)
  44. Lu MC, Yu CL, Yu HC, Huang HB, Koo M, Lai NS* (2016) Anti-citrullinated protein antibodies promote apoptosis of mature human Saos-2 osteoblasts via cell-surface binding to citrullinated heat shock protein 60. Immunobiology 221(1):76–83. doi:10.1016/j.imbio.2015.07.019
  45. Lu MC, Hsieh MC, Koo M*, Lai NS* (2016) Risk of Sjögren’s syndrome in Taiwanese female adults with irregular menstrual cycle: A population-based case control study. Rheumatology International 36(1):155–160. doi:10.1007/s00296-015-3324-z
  46. Wu LF, Koo M* (2016) Randomized controlled trial of a six-week spiritual reminiscence intervention on hope, life satisfaction, and spiritual well-being in elderly with mild and moderate dementia. International Journal of Geriatric Psychiatry 31(2):120–127. doi:10.1002/gps.4300
  47. Koo M, Lin SC* (2016) The image of nursing – a glimpse of the Internet. Japan Journal of Nursing Science 13(4):496–501. doi:10.1111/jjns.12125
  48. Yu IL, Yu ZR, Koo M*, Wang BJ* (2016) A continuous fractionation of ginsenosides and polysaccharides from Panax gingseng using supercritical carbon dioxide technology. Journal of Food Processing and Preservation 40(4):743–748. doi:10.1111/jfpp.12655
  49. Wu LF, Koo M*, Liao YC, Chen YM, Yeh DC (2016) Development and validation of the spiritual care needs inventory for acute care hospital patients in Taiwan. Clinical Nursing Research 25(6):590–606. doi:10.1177/1054773815579609
  50. Chen CY, Wu FJ, Chen CM, Hsu H, Koo M* (2015) Effects of horticultural therapy activity programme for alleviating work-related stress and improving well-being of nursing staff (in Chinese) Journal of the Taiwan Society for Horticultural Science 61(4):281–291.
  51. Lin SC, Tsai KW, Shih HS, Wang SY, Chen MW, Koo M* (2015) Treatment and nursing care of elderly patients with dementia. (in Chinese) Leadership Nursing 16(3):13–19.
  52. Lin MS, Yu ZR, Wang BJ, Wang CC, Weng YM, Koo M* (2015) Bioactive constituent characterization and antioxidant activity of Ganoderma lucidum extract fractionated by supercritical carbon dioxide. Sains Malaysiana 44(12):1685–1691.
  53. Hsueh YC, Wang BJ, Yu ZR, Wang CC, Koo M* (2015) Optimization of a continuous preparation method of Arthrospira (Spirulina) platensis γ-linolenic acid by supercritical carbon dioxide technology using response surface methodology. Sains Malaysiana 44(12):1739–1744.
  54. Ho HC, Koo M, Tsai TH, Chen CY* (2015) Effects of a mindfulness meditation course on learning and cognitive performance among university students in Taiwan. Evidence-Based Complementary and Alternative Medicine 2015:254358. doi:10.1155/2015/254358 (Koo & Ho contributed equally to this work)
  55. Lu MC, Liu KC, Lai NS*, Koo M* (2015) Higher incidence of rheumatoid arthritis in patients with symptomatic osteoarthritis or osteoarthritis-related surgery: a nationwide population-based case-control study in Taiwan. BMJ Open 5:e008513. doi:10.1136/bmjopen-2015-008513 (Koo & Lai are co-corresponding authors)
  56. Huang CH, Lu MC, Koo M* (2015) Dietary patterns of habitual vegetarians – findings from the 2009 National Health Interview Survey  (in Chinese) Nutritional Science Journal 40(3):94–106.
  57. Lu MC, Koo M*, Lai NS* (2015) Clinimetric properties of the Chinese version of the early inflammatory arthritis detection tool. BMC Musculoskeletal Disorders 16:243. doi:10.1186/s12891-015-0706-z
  58. Hsiao IY, Chien CY, Chen CY, Lin TK, Koo M* (2015) Predictors of no improvement in left ventricular ejection fraction among patients with congestive heart failure one year after completing a six-month case management program: a prospective observational study. Tzu Chi Medical Journal 27(4):164–169. doi:10.1016/j.tcmj.2015.07.004
  59. Koo M, Tsai KW, Lin SC* (2015) Evidence-based medicine regarding the nonpharmacological approaches for the alleviation of chronic pain in older adults. (in Chinese) Taiwan Geriatrics and Gerontology 10(2):63–72.
  60. Lai NS, Yu HC, Yu CL, Koo M, Huang HB, Lu MC* (2015) Anti-citrullinated protein antibodies suppress let-7a expression in monocytes from patients with rheumatoid arthritis and facilitate the inflammatory responses in rheumatoid arthritis. Immunobiology 220(12):1351–1358. doi:10.1016/j.imbio.2015.07.007
  61. Lin MC, Yeh YC, Koo M* (2015) Pattern and factors associated with massage therapy and complementary therapies utilization on relieving work-related fatigue among telephone customer services personnel in telecommunications industry.  (in Chinese) Evidence-Based Natural Medicine 1(2):17–26.
  62. Koo M, Peng SM, Chang RY* (2015) Humor therapy is not joking – evidence based research in humor therapy  (in Chinese) Evidence-Based Natural Medicine 1(2):35–47.
  63. Lu MC, Lai CL, Tsai CC, Koo M*, Lai NS* (2015) Increased risk of pulmonary and extrapulmonary tuberculosis in patients with rheumatic diseases. International Journal of Tuberculosis and Lung Disease 19(12):1500–1506. (Koo & Lai are co-corresponding authors)
  64. Koo M, Chen CH, Tsai KW, Lu MC, Lin SC* (2015) Ambulatory medical services utilization for menstrual disorders among female personnel of different medical professions in Taiwan: a nationwide retrospective cohort study. BMC Women’s Health 15:66. doi:10.1186/s12905-015-0220-3
  65. Koo M, Lu MC, Lai CY* (2015) Writing review articles for medical journals. (in Chinese) Formosan Journal of Medicine 19(5):542–549. doi:10.6320/FJM.2015.19(5).13
  66. Lin SC, Tsai KW, Chen MW, Koo M* (2015) Factors associated with health examination utilization among community-dwelling elderly Taiwanese: analysis of the 2009 National Health Interview Survey  (in Chinese) Cheng Ching Medical Journal 11(3):10–21.
  67. Tsai KW, Lin SC, Lu MC, Koo M*(2015). Factors associated with vegetarian dietary habits in Taiwanese adults – analysis of the 2009 National Health Interview Survey  (in Chinese) Journal of Medicine and Health 4(2):41–51.
  68. Wang SY, Liu LC, Lu MC, Koo M* (2015) Comparisons of musculoskeletal disorders among ten different medical professions in Taiwan: A nationwide, population-based study. PLOS ONE 10(4): e0123750. doi:10.1371/journal.pone.0123750
  69. Lai NS, Tsai TY, Koo M, Lu MC* (2015) Increased risk of rheumatoid arthritis in patients with allergic diseases: a nationwide population-based cohort study. Allergy and Asthma Proceedings 36(5):99–103. doi:10.2500/aap.2015.36.3871
  70. Huang CF, Chen CT, Wang PM, Koo M* (2015) Betel-quid, alcohol, and cigarette use were associated with lipid accumulation product among male factory workers in Taiwan. International Health 7(3):218–222. doi:10.1093/inthealth/ihu065
  71. Hsueh YC, Yu ZR, Wang CC, Koo M*, Wang BJ* (2015) Supercritical CO2 extraction of γ-linolenic acid from Spirulina platensis. Applied Mechanics and Materials 764–765: 92-97. doi:10.4028/www.scientific.net/AMM.764-765.92 (Koo & Wang are co-corresponding authors)
  72. Chen JC, Koo M, Hwang JH* (2015) Risks of peripheral arterial occlusive disease in patients with obstructive sleep apnea: a population-based case-control study. Clinical Otolaryngology 40(5):437–442. doi:10.1111/coa.12393 (Koo & Chen contributed equally to this work)
  73. Koo M, Hwang JH* (2015) Risk of sudden sensorineural hearing loss in patients with common preexisting sensorineural hearing impairment: a population-based study in Taiwan. PLOS ONE 10(3): e0121190. doi:10.1371/journal.pone.0121190
  74. Wu LF, Koo M*, Tseng HC, Liao YC, Chen YM (2015) Concordance between nurses’ perception of their ability to provide spiritual care and the identified spiritual needs of hospitalized patients: A cross-sectional observational study. Nursing and Health Sciences 17(4):426–433. doi: 10.1111/nhs.12210
  75. Lin SC, Tsai KW, Chen MW, Koo M* (2015) Prevention and management of geriatric sarcopenia. (in Chinese) Tzu Chi Nursing Journal 14(2):62–68.
  76. Chiang JK, Koo M, Kao YH* (2015) Development of a user-friendly graphic tool to estimate individualized survival curves for advanced cancer patients in hospice care. Supportive Care in Cancer 31(1):29–35. (Kao & Koo contributed equally to this work)
  77. Koo M, Lu MC, Lai CY* (2015) Tabular displays of data in medical journal articles.  (in Chinese) Formosan Journal of Medicine 19(3):311–315. doi:10.6320/FJM.2015.19(3).12
  78. Lu MC, Yin WY, Liu SQ, Koo M, Tung CH, Huang KY, Lai NS* (2015) Increased prevalence of JC polyomavirus viruria was associated with arthritis/arthralgia in patients with systemic lupus erythematosus. Lupus 24(7):687–694. doi:10.1177/0961203314559629 [2014 IF=2.20]
  79. Hsieh YH*, Koo M (2014) Bowel preparation: Is endoscopic administration worth the extra risk? (editorial) Digestive Diseases and Sciences 60(1):1–3. doi:10.1007/s10620-014-3441-7
  80. Lai CY, Lu MC, Koo M* (2014) Analysis of patient-oriented features on the websites of medical centers, regional hospitals, and district hospitals in Taipei City, Taiwan. Journal of Taiwan Association for Medical Informatics 23(3):13–24.
  81. Lee MH, Koo M, Yeh YC* (2014) Factors associated with sleep quality among shiftwork firefighters. (in Chinese) Journal of Occupational Safety and Health (Koo & Lee contributed equally to this work) 22(3):224–234.
  82. Koo M, Liang KL, Jiang RS, Tsao H, Yeh YC* (2014) Association between disease-specific quality of life and complementary medicine use in patients with rhinitis in Taiwan: a cross-sectional survey study. Evidence-Based Complementary and Alternative Medicine 2014:958524. doi:10.1155/2014/958524 (Koo & Liang contributed equally to this work)
  83. Yin WY, Koo M, Lee MC, Lu MC* (2014) Incidence of non-Hodgkin lymphomas and the ten most commonly diagnosed cancers following heart transplantation: a nationwide population-based study in Taiwan. Transplantation (Yin & Koo contributed equally to this work) 98(7):e71–73. doi:10.1097/TP.0000000000000374
  84. Lu MC, Yan ST, Yin WY, Koo M*, Lai NS* (2014) Risk of rheumatoid arthritis in patients with type 2 diabetes: a nationwide population-based case-control study. PLOS ONE 9(7):e101528. doi:10.1371/journal.pone.0101528 (Koo & Lai are co-corresponding authors)
  85. Tsai KW, Lin SC, Koo M* (2014) Factors associated with the uptake of seasonal influenza vaccination among elderly in Taiwan – Analysis of the 2009 National Health Interview Survey. (in Chinese) Taiwan Geriatrics and Gerontology 9(1):28–41.
  86. Lai NS, Tsai TY, Koo M, Huang KY, Tung CH, Lu MC* (2014) Patterns of ambulatory medical care utilization and rheumatologist consultation predating the diagnosis of systemic lupus erythematosus: A national population-based study. PLOS ONE 9(7):e101485. doi:10.1371/journal.pone.0101485
  87. Lu MC, Fa WH, Tsai TY, Koo M*, Lai NS* (2014) Increased utilization of eye disorder-related ambulatory medical services prior to the diagnosis of Sjögren syndrome in female patients. BMJ Open 4(5):e003862. doi:10.1136/bmjopen-2013-003862 (Koo & Lai are co-corresponding authors)
  88. Lin SC, Koo M*, Tsai KW (2014) Association between Helicobacter pylori infection and risk of osteoporosis in elderly Taiwanese women with upper gastrointestinal diseases – a retrospective patient record review. Gastroenterology Research and Practice 2014: 814756. doi:10.1155/2014/814756
  89. Chen MJ, Lin JS, Chen CY*, Koo M* (2014) Association between body constitution of Chinese medicine and acne in male university students. (in Chinese) Journal of Chinese Medicine 25(2):189–203. doi:10.3966/101764462014122502005
  90. Koo M* (2014) Complementary and alternative medicine on Wikipedia: opportunities for improvement. Evidence-Based Complementary and Alternative Medicine 2014:105186. doi:10.1155/2014/105186
  91. Lu MC, Jheng CH, Tsai TY, Koo M*, Lai NS* (2014) Increased dental visits in patients prior to diagnosis of primary Sjögren’s syndrome: a longitudinal population-based study in Taiwan. Rheumatology International 34(11): 1555–1561. doi:10.1007/s00296-014-3003-5. (Koo & Lai are co-corresponding authors)
  92. Hsieh YH, Koo M, Leung FW* (2014) A patient-blinded randomized, controlled trial comparing air insufflation, water immersion and water exchange during minimally sedated colonoscopy. American Journal of Gastroenterology 109(9):1390–1400. doi:10.1038/ajg.2014.126
  93. Chen HM, Tsai MT, Wu R, Koo M* (2014) Outcomes of a visual training program on children with myopia – a pilot study. Evidence-based Natural Medicine 1(1):15–21.
  94. Yang SW, Koo M* (2014) Use of complementary and alternative medicine for the management of HIV/AIDS: a psychoneuroimmunology perspective.](in Chinese) Evidence-based Natural Medicine 1(1):23–36.
  95. Koo M, Lu MC, Tsai TY, Lai CY* (2014) Secondary data analysis: research applications for healthcare providers. (in Chinese) Formosan Journal of Medicine 18(4):471–479. doi:10.6320/FJM.2014.18(4).13
  96. Lu MC, Yin WY, Tsai TY, Koo M*, Lai NS* (2013) Increased risk of primary Sjögren’s syndrome in female patients with thyroid disorders: a longitudinal population-based study in Taiwan. PLOS ONE 8(10): e77210. doi:10.1371/journal.pone.0077210 (Koo & Lai are co-corresponding authors)
  97. Lai NS, Tsai TY, Li CY, Koo M, Yu CL, Lu MC* (2014) Increased frequency and costs of ambulatory medical care utilization prior to the diagnosis of rheumatoid arthritis: a national population-based study. Arthritis Care & Research 66(3):371–378. doi:10.1002/acr.22146
  98. Hsu TK, Koo M, Yeh YC* (2014) Factors associated with the use of complementary medicine in emergency department physicians in Taiwan. (in Chinese) Formosan Journal of Medicine18:153–162. doi:10.6320/FJM.2014.18(2).03 (Koo & Hsu contributed equally to this manuscript)
  99. Hsu TK, Koo M, Yeh YC* (2013) Investigation of factors associated with sleep quality among male emergency department physicians in Taiwan. (in Chinese) Show Chwan Medical Journal 12(1,2):1–9. (Hsu & Koo contributed equally to this manuscript)
  100. Ochirkhuyag U, Koo M, Wu HC*, Yeh YC* (2013) Changes in health status and health services utilization of Mongolian undergraduate and graduate students in Taiwan. Journal of Medicine and Health 2(2):53–62. (Koo & Ochirkhuyag contributed equally to this manuscript)
  101. Koo M, Liang KL, Tsao H, Yen TT, Jiang RS*, Yeh YC* (2013) Factors associated with the use of different treatment modalities among patients with upper airway diseases in Taiwan: a cross-sectional survey study. Journal of Allergy 2013:720879. doi:10.1155/2013/720879
  102. Chiang JK, Kuo TBJ, Fu CH*, Koo M* (2013) Predicting 7-day survival using heart rate variability in hospice patients with non-lung cancers. PLOS ONE 8(7): e69482. doi:10.1371/journal.pone.0069482 (Koo & Fu are co-corresponding authors)
  103. Koo M, Lai NS, Chiang JK* (2013) Short duration of sleep is associated with hyperleptinemia in Taiwanese adults. Journal of Clinical Sleep Medicine 9(10):1049–1055. doi:10.5664/jcsm.3080
  104. Koo M, Lin YC* (2013) A guide to oral presentations in medical and nursing conferences. (in Chinese) Formosan Journal of Medicine 17(5):575–583. doi:10.6320/FJM.2013.17(5).16
  105. Lin SC, Koo M, Chen MW, Tsai KW* (2013) Prevention and care of osteoporosis in the elderly.  (in Chinese) Tzu Chi Nursing Journal 12(4):58–62.
  106. Liang KL, Jiang RS, Wang RC, Koo M, Chen SC, Huang WC, Yeh YC* (2013) Upper-airway inflammation exacerbates bronchial hyperreactivity in mouse models of rhinosinusitis and allergic asthma. International Forum of Allergy & Rhinology 3(7):532–542. doi:10.1002/alr.21160
  107. Chang RY, Koo M*, Lu YC, Lin YF (2013) Effects of habitual Tai Chi exercise on adiponectin, glucose homeostasis, lipid profile, and atherosclerotic burden in individuals with cardiovascular risk factors. Journal of Alternative and Complementary Medicine 19(8):697–703. doi:10.1089/acm.2011.0966
  108. Lin SC, Tsai KW, Chen MW, Koo M* (2013) Association between fatigue and Internet addiction in female hospital nurses. Journal of Advanced Nursing 69(2):374–383. doi:10.1111/j.1365-2648.2012.06016.x