Doctor of Philosophy, Epidemiology, Department of Public Health Sciences, University of Toronto, Canada, 2000.
Master of Science, Nutritional Sciences, University of Toronto, Canada, 1990.
Bachelor of Science, Nutritional Sciences, University of Toronto, Canada, 1987.
Primary Teaching Responsibilities
Professional Summary & Appointments
Adjunct Professor: Dalla Lana School of Public Health, University of Toronto (08/2005 – present)
Research Fellow: Department of Medical Research, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taiwan (11/2012-present)
Director and Associate Professor: Graduate Institute of Natural Healing Sciences, Nanhua University, Taiwan (8/2005 – 8/2010)
Chair and Associate Professor: Department of Natural Biotecnhnology, Nanhua University, Taiwan (08/2006 – 07/2008)
Assistant Professor: Department of Public Health Sciences, University of Toronto (09/2001 – 06/2005)
Honours & Awards
Current Research Projects
Secondary data anaylsis of the Taiwan's National Health Insurance Research Database
Hsueh YC, Yu ZR, Wang CC, Koo M*, Wang BJ*. Optimization of a continuous preparation method of Arthrospira (Spirulina) platensis γ-linolenic acid by supercritical carbon dioxide technology using response surface methodology. Sains Malaysian (Koo & Wang are co-corresponding authors) (accepted)
Lin SC, Tsai KW, Chen MW, Koo M* Factors associated with the utilization of health examinations by community-dwelling elderly Taiwanese: an analysis of the 2009 National Health Interview Survey (in Chinese) Cheng Ching Medical Journal 11(3):10-21.
Wu LF, Koo M* (2015) Effects of spiritual reminiscence on hope, life satisfaction, and spiritual well-being in elderly with mild and moderate dementia. International Journal of Geriatric Psychiatry doi:10.1002/gps.4300 [2013 IF=3.09]
Wang SY, Liu LC, Lu MC, Koo M* (2015) Comparisons of musculoskeletal disorders among ten different medical professions in Taiwan: A nationwide, population-based study. PLOS ONE 10(4):e0123750. doi:10.1371/journal.pone.0123750 [2013 IF=3.54]
Lai NS, Tsai TY, Koo M, Lu MC* (2015) Increased risk of rheumatoid arthritis in patients with allergic diseases: a nationwide population-based cohort study. (accepted) Allergy and Asthma Proceedings [2013 IF=3.35]
Huang CF, Chen CT, Wang PM, Koo M* (2015) Betel-quid, alcohol, and cigarette use were associated with lipid accumulation product among male factory workers in Taiwan. International Health 7(3):218-222. doi:10.1093/inthealth/ihu065 [2013 IF=1.13]
Hsueh YC, Yu ZR, Wang CC, Koo M*, Wang BJ* (2015) Supercritical CO2 extraction of γ-linolenic acid from Spirulina platensis.Applied Mechanics and Materials 764-765:92-97. doi: 10.4028/www.scientific.net/AMM.764-765.92 (Koo & Wang are co-corresponding authors)
Chen JC, Koo M, Hwang JH (2015) Risks of peripheral arterial occlusive disease in patients with obstructive sleep apnea: a population-based case-control study. Clinical Otolaryngology doi:10.1111/coa.12393 (Koo & Chen contributed equally to this work) [2013 IF=2.27]
Wu LF, Koo M*, Liao YC, Chen YM, Yeh DC (2015) Development and validation of the spiritual care needs inventory for acute care hospital patients in Taiwan. (accepted, Epub ahead of print) Clinical Nursing Research [2013 IF=0.87]
Koo M, Hwang JH* (2015) Risk of sudden sensorineural hearing loss in patients with common preexisting sensorineural hearing impairment: a population-based study in Taiwan. PLOS ONE 10(3):e0121190. doi:10.1371/journal.pone.0121190 [2013 IF=3.54]
Wu LF, Koo M*, Tseng HC, Liao YC, Chen YM (2015) Concordance between nurses’ perception of their ability to provide spiritual care and the identified spiritual needs of hospitalized patients: A cross-sectional observational study. (accepted) Nursing and Health Sciences [2013 IF=0.85]
Lin SC, Tsai KW, Chen MW, Koo M* (2015) Prevention and management of geriatric sarcopenia. (in Chinese) Tzu Chi Nursing Journal 14(2):62-68.
Chiang JK, Koo M, Kao YH* (2015) Development of a user-friendly graphic tool to estimate individualized survival curves for advanced cancer patients in hospice care. Supportive Care in Cancer (Kao & Koo contributed equally to this work)(accepted) [2013 IF=2.50]
Koo M, Lu MC, Lai CY*(2015) Tabular displays of data in medical journal articles. (in Chinese) Formosan Journal of Medicine (accepted)
Lu MC, Yin WY, Liu SQ, Koo M, Tung CH, Huang KY, Lai NS* (2014) Increased prevalence of JC polyomavirus viruria was associated with arthritis/arthralgia in patients with systemic lupus erythematosus. Lupus 24(7):687-694. doi:10.1177/0961203314559629 [2013 IF=2.48]
Hsieh YH*, Koo M (2014) Bowel preparation: Is endoscopic administration worth the extra risk? (editorial) Digestive Diseases and Scienes 60(1):1-3. doi:10.1007/s10620-014-3441-7 [2013 IF=2.55]
Koo M, Lu MC, Lai CY*. Writing review articles for medical journals. (in Chinese) (accepted) Formosan Journal of Medicine
Lai CY, Lu MC, Koo M* (2014) Analysis of patient-oriented features on the websites of medical centers, regional hospitals, and district hospitals in Taipei City, Taiwan. Journal of Taiwan Association for Medical Informatics 23(3):13-24.
Lin SC, Tsai KW, Shih HS, Wang SY, Chen MW, Koo M* (2015) Treatment and nursing care of elderly patients with dementia. (in Chinese) Leadership Nursing (accepted)
Lee MH, Koo M, Yeh YC* (2014) Factors associated with sleep quality among shiftwork firefighters. (in Chinese) Journal of Occupational Safety and Health (Koo & Lee contributed equally to this work) 22(3):224-234.
Koo M, Liang KL, Jiang RS, Tsao H, Yeh YC* (2014) Association between disease-specific quality of life and complementary medicine use in patients with rhinitis in Taiwan: a cross-sectional survey study. Evidence-Based Complementary and Alternative Medicine 2014:958524. doi:10.1155/2014/958524 (Koo & Liang contributed equally to this work) [2013 IF=2.18]
Yin WY, Koo M, Lee MC, Lu MC* (2014) Incidence of non-Hodgkin lymphomas and the ten most commonly diagnosed cancers following heart transplantation: a nationwide population-based study in Taiwan. Transplantation (Yin & Koo contributed equally to this work) 98(7):e71-73. doi: 10.1097/TP.0000000000000374 [2013 IF=3.54]
Lu MC, Yan ST, Yin WY, Koo M*, Lai NS* (2014) Risk of rheumatoid arthritis in patients with type 2 diabetes: a nationwide population-based case-control study. PLOS ONE 9(7):e101528. doi:10.1371/journal.pone.0101528 (Koo & Lai are co-corresponding authors) [2013 IF=3.54]
Tsai KW, Lin SC, Koo M* (2014) Factors associated with the uptake of seasonal influenza vaccination among elderly in Taiwan – Analysis of the 2009 National Health Interview Survey. (in Chinese) Taiwan Geriatrics and Gerontology 9(1):28-41.
Lai NS, Tsai TY, Koo M, Huang KY, Tung CH, Lu MC* (2014) Patterns of ambulatory medical care utilization and rheumatologist consultation predating the diagnosis of systemic lupus erythematosus: A national population-based study. PLOS ONE 9(7):e101485. doi:10.1371/journal.pone.0101485 [2013 IF=3.54]
Lu MC, Fa WH, Tsai TY, Koo M*, Lai NS* (2014) Increased utilization of eye disorder-related ambulatory medical services prior to the diagnosis of Sjögren syndrome in female patients. BMJ Open 4(5):e003862. doi:10.1136/bmjopen-2013-003862 (Koo & Lai are co-corresponding authors) [2012 IF=1.58]
Lin SC, Koo M*, Tsai KW (2014) Association between Helicobacter pylori infection and risk of osteoporosis in elderly Taiwanese women with upper gastrointestinal diseases – a retrospective patient record review. Gastroenterology Research and Practice 2014: 814756. doi:10.1155/2014/814756 [2012 IF=1.62]
Chen MJ, Lin JS, Chen CY*, Koo M* (2014) Association between body constitution of Chinese medicine and acne in male university students. (in Chinese) Journal of Chinese Medicine 25(2):189-203. doi:10.3966/101764462014122502005
Koo M* (2014) Complementary and alternative medicine on Wikipedia: opportunities for improvement. Evidence-Based Complementary and Alternative Medicine 2014:105186. doi:10.1155/2014/105186 [2012 IF=1.72]
Lu MC, Jheng CH, Tsai TY, Koo M*, Lai NS* (2014) Increased dental visits in patients prior to diagnosis of primary Sjögren’s syndrome: a longitudinal population-based study in Taiwan. Rheumatology International 34(11): 1555-1561. doi:10.1007/s00296-014-3003-5. (Koo & Lai are co-corresponding authors) [2012 IF=2.22]
Hsieh YH, Koo M, Leung FW* (2014) A patient-blinded randomized, controlled trial comparing air insufflation, water immersion and water exchange during minimally sedated colonoscopy. American Journal of Gastroenterology 109(9):1390-1400. doi:10.1038/ajg.2014.126 [2013 IF=9.21]
Chen HM, Tsai MT, Wu R, Koo M* (2014) Outcomes of a visual training program on children with myopia – a pilot study. Evidence-based Natural Medicine 1(1):15-21.
Yang SW, Koo M* (2014) Use of complementary and alternative medicine for the management of HIV/AIDS: a psychoneuroimmunology perspective. (in Chinese)Evidence-based Natural Medicine 1(1):23-36.
Koo M, Lu MC, Tsai TY, Lai CY* (2014) Secondary data analysis: research applications for healthcare providers. (in Chinese) Formosan Journal of Medicine 18(4):471-479. doi:10.6320/FJM.2014.18(4).13
Lu MC, Yin WY, Tsai TY, Koo M*, Lai NS*(2013) Increased risk of primary Sjögren's syndrome in female patients with thyroid disorders: a longitudinal population-based study in Taiwan. PLOS ONE 8(10): e77210. (Koo & Lai are co-corresponding authors) [2012 IF=3.73]
Lai NS, Tsai TY, Li CY, Koo M, Yu CL, Lu MC* (2014) Increased frequency and costs of ambulatory medical care utilization prior to the diagnosis of rheumatoid arthritis: a national population-based study. Arthritis Care & Research 66(3):371-378. doi:10.1002/acr.22146 [2012 IF=3.73]
Hsu TK, Koo M, Yeh YC* (2014) Factors associated with the use of complementary medicine in emergency department physicians in Taiwan. (in Chinese) Formosan Journal of Medicine18:153-162. doi:10.6320/FJM.2014.18(2).03 (Koo & Hsu contributed equally to this manuscript)
Hsu TK, Koo M, Yeh YC* (2013) Investigation of factors associated with sleep quality among male emergency department physicians in Taiwan. (in Chinese) Show Chwan Medical Journal 12(1,2):1-9. (Hsu & Koo contributed equally to this manuscript)
Ochirkhuyag U, Koo M, Wu HC*, Yeh YC* (2013) Changes in health status and health services utilization of Mongolian undergraduate and graduate students in Taiwan. Journal of Medicine and Health 2(2):53-62. (Koo & Ochirkhuyag contributed equally to this manuscript)
Koo M, Liang KL, Tsao H, Yen TT, Jiang RS*, Yeh YC* (2013) Factors associated with the use of different treatment modalities among patients with upper airway diseases in Taiwan: a cross-sectional survey study. Journal of Allergy 2013:720879. doi:10.1155/2013/720879
Chiang JK, Kuo TBJ, Fu CH*, Koo M* (2013) Predicting 7-day survival using heart rate variability in hospice patients with non-lung cancers. PLOS ONE 8(7): e69482. doi:10.1371/journal.pone.0069482 (Koo & Fu are co-corresponding authors) [2012 IF=3.73]
Koo M, Lai NS, Chiang JK* (2013) Short duration of sleep is associated with hyperleptinemia in Taiwanese adults. Journal of Clinical Sleep Medicine 9(10):1049-1055. [2012 IF=2.93]
Koo M, Lin YC*(2013) A guide to oral presentations in medical and nursing conferences. (in Chinese) Formosan Journal of Medicine 17(5):575-583.
Lin SC, Koo M, Chen MW, Tsai KW* (2013) Prevention and care of osteoporosis in the elderly. (in Chinese) Tzu Chi Nursing Journal 12(4):58-62.
Liang KL, Jiang RS, Wang RC, Koo M, Chen SC, Huang WC, Yeh YC* (2013) Upper-airway inflammation exacerbates bronchial hyperreactivity in mouse models of rhinosinusitis and allergic asthma. International Forum of Allergy & Rhinology 3(7):532-542. [2013 IF=2.37]
Chang RY, Koo M*, Lu YC, Lin YF (2013) Effects of habitual Tai Chi exercise on adiponectin, glucose homeostasis, lipid profile, and atherosclerotic burden in individuals with cardiovascular risk factors. Journal of Alternative and Complementary Medicine 19(8):697-703. [2011 IF=1.59]
Lin SC, Tsai KW, Chen MW, Koo M* (2013) Association between fatigue and Internet addiction in female hospital nurses. Journal of Advanced Nursing 69(2):374-383. [2010 IF=1.54]
Chiang JK, Koo M* (2012) Lipid accumulation product: a simple and accuracy index for predicting metabolic syndrome in Taiwanese people aged 50 and over. Cardiovascular Disorder. 12:78. [2012 IF=1.52]
Chang JK, Koo M, Kao YY, Chiang JK* (2012) Association of sleep duration and insulin resistance in Taiwanese vegetarians. BMC Public Health 12(1):666. [2011 IF=2.00]
Lai CY, Lai CM, Chen CY, Koo M* (2012) Factors associated with non-utilization of mammographic screening services in middle-aged and elderly women in Taiwan. (in Chinese) Journal of Nursing Research 59(2):61-71.
Koo M*, Norman CD, Chang HM (2012) Psychometric evaluation of Chinese version of the eHealth Literacy Scale (eHEALS) in school age children. International Electronic Journal of Health Education 15:29-36.
Huang CF, Wang SF, Yeh YC, Lee MH, Chen SC, Koo M* (2012) Prevalence and factors associated with metabolic syndrome in middle-aged adults and elderly in southern Taiwan. (in Chinese) Tzu Chi Nursing Journal 11(1):72-84.
Ku CF, Koo M* (2012) Association of distress symptoms and use of complementary medicine among patients with cancer. Journal of Clinical Nursing 21(5-6):736-744. doi:10.1111/j.1365-2702.2011.03884.x [2009 IF=1.20]
Chiang JK, Lai NS, Chang JK, Koo M* (2011) Predicting insulin resistance using the triglyceride-to-high-density lipoprotein cholesterol ratio in Taiwanese adults. Cardiovascular Diabetology 10:93. doi:10.1186/1475-2840-10-93 [2011 IF=3.35]
Koo M, Lee MH, Chang YY, Huang CF, Chen SC, Yeh YC* (2011) Factors associated with self-care behaviors in middle-aged adults and elderly with diabetes. (in Chinese) Journal of Nursing Research 58(5):43-52.
Lin YC, Yeh YC, Lai YL, Koo M* (2011) Physicians and nurses’ attitudes towards complementary medicine use among patients in hospice wards. (in Chinese) Taiwan Journal of Hospice Palliative Care 16(2):27-41.
Koo M, Lai CY, Lin JH* (2011) Writing and publishing of medical and nursing scientific posters. (in Chinese) Formosan Journal of Medicine 15(6):668-676.
Yeh YC, Chen SC, Huang CF, Lee MH, Koo M* (2011) Writing and publishing in medical and nursing journals. (in Chinese) Formosan Journal of Medicine 15(2):217-224.
Chen HM, Wang SF, Huang CF, Chau TT, Koo M* (2011) Effect of healthy lifestyle intervention on hypercholesterolemia and other risk factors of metabolic syndrome in females. (in Chinese) Taiwan Journal of Family Medicine 20(4):167-177.
Koo M, Chang YY, Lee MH, Huang CF, Chen SC, Yeh YC* (2011) Factors associated with the use of complementary and alternative medicine in middle-aged adults and elderly. (in Chinese) Taiwan Geriatrics and Gerontology 6(1):29-42.
Chiang JK, Fu CH, Kuo TBJ, Koo M* (2011) Association between frequency domain heart rate variability and unplanned readmission to hospital in geriatric patients. BMC Public Health 11:137. doi:10.1186/1471-2458-11-137 [2009 IF=2.22]
Chang RY, Koo M, Ho MY, Lin ZZ, Yu ZR, Wang BJ* (2011) Effect of Tai Chi on adiponectin and glucose homeostasis in individuals with cardiovascular risk factors. European Journal of Applied Physiology 111(1):57-66. doi:10.1007/s00421-010-1628-y [2009 IF=2.05] (Chang & Koo contributed equally to this manuscript)
Han CY, Lin JC, Koo M, Yu ZR, Shy IC* (2010) Cervical cancer screening in female prison inmates in Taichung. Taiwan Journal of Family Medicine 20(1):38-45.
Koo M*, Tucker A, Cotterchio M, Kreiger N, McLaughlin J, Gallinger S (2010) Randomized controlled trial of the use of an educational cancer website to increase cancer patient’s participation into a research study. Asian Journal of Arts and Sciences 1(1):17-28.
Peng SM, Koo M*, Kuo JC (2010) Effect of group music activity as an adjunctive therapy on psychotic symptoms in patients with schizophrenia. Archives of Psychiatric Nursing 24(6):429-434. doi:10.1016/j.apnu.2010.04.001 [2009 IF=0.90]
Lin SC, Tsai KW, Chiang JK, Koo M* (2010) Factors associated with hospital readmissions of elderly residents in long-term care facilities. (in Chinese) Tzu Chi Nursing Journal 9(3):92-100.
Chang RY, Koo M*, Kan CB, Yu ZR, Chu IT (2010) Effect of Tai Chi rehabilitation on heart rate responses in patients with coronary artery disease. American Journal of Chinese Medicine 38(3):461-472. [2009 IF=1.42]
Chiang JK, Cheng YH, Koo M, Kao YH*, Chen CY (2010) A computer-assisted model for predicting probability of dying within 7 days of hospice admission in patients with terminal cancer. Japanese Journal of Clinical Oncology 40(5):449-455. doi:10.1093/jjco/hyp188. [2009 IF=1.50]
Chiang JK, Koo M, Kuo TBJ, Fu CH* (2010) Association between cardiovascular autonomic functions and time to death in patients with terminal hepatocellular carcinoma. Journal of Pain and Symptom Management 39(4):673-679. doi:10.1016/j.jpainsymman.2009.09.014 [2009 IF=2.42]
Shih MZ, Yang YH, Koo M* (2009) A meta-analysis of hypnosis in the treatment of depressive symptoms: A brief communication. International Journal of Clinical and Experimental Hypnosis 57(4):431-442. [2009 SSCI IF=1.25]
Hsu CW, Chen MH, Koo M* (2009) The investigation of the relief time in Shang-Han-Lun. (in Chinese) Journal of Chinese Medicine 20(1,2):47-64.
Peng SM, Koo M*, Yu ZR (2009) Effects of music and essential oil inhalation on cardiac autonomic balance in healthy individuals. Journal of Alternative and Complementary Medicine 15(1):53-57. doi:10.1089/acm.2008.0243 [2009 IF=1.69]
Chang RY*, Koo M, Yu ZR, Kan CB, Chu IT, Hsu CT, Chen CY (2008) The effect of T'ai Chi exercise on autonomic nervous function of patients with coronary artery disease. Journal of Alternative and Complementary Medicine 14(9):1107-1113. doi:10.1089/acm.2008.0166 [2009 IF=1.69]
Wang SF, Koo M, Chiang JK* (2008) The willingness in participating home care services for discharged patients among volunteers in health stations in Chiayi county. (in Chinese) Formosan Journal of Medicine 12(1):7-15.
Lin CC, Pumsanguan W, Koo MMO, Huang HB, Lee MS* (2007) Radiation protective effects of Cordyceps sinensis in blood cells. Tzu Chi Medical Journal 19(4):226-232.
Koezuka N*, Koo M, Allison KR, Adlaf EM, Dwyer JJM, Faulkner G, Goodman J (2006) The relationship between sedentary activities and physical inactivity among adolescents – Results from the Canadian Community Health Survey. Journal of Adolescent Health 39(4):515-522. [2009 IF=3.33]
Koo M*, Skinner H (2005) Challenges of Internet recruitment: A case study with disappointing results. Journal of Medical Internet Research 7:e6. [2009 IF=3.92]
Koo M*, Skinner H (2003) Improving web searches: Case study of quit-smoking Web sites for teenagers. Journal of Medical Internet Research 5:e28. [2009 IF=3.92]
Koo MM*, Rohan TE, Jain M, McLaughlin JR, Corey PN (2002) A cohort study of dietary fibre intake and menarche. Public Health Nutrition 5(2):353-360. [2009 IF=2.75]
Koo MM, Rohan TE* (2000) Use of World Wide Web-based directories for tracing subjects in epidemiologic studies. American Journal of Epidemiology 152(9):889-894. [2009 IF=5.59]
Koo MM, Rohan TE* (1999) Comparison of four habitual physical activity questionnaires in girls aged 7-15 yr. Medicine and Science in Sports and Exercise 31(3):421-427. [2009 IF=3.71]
Koo MM, Rohan TE* (1997) Accuracy of short-term recall of age at menarche. Annals of Human Biology 24(1):61-64. [2009 IF=1.06]
Koo M, Rohan T* (1996) Types of advance notification in reminder letters and response rates. Epidemiology 7:215-216. [2009 IF=5.51]
Koo M, Rohan T* (1995) Printed signatures and response rates. Epidemiology 6:568. [2009 IF=5.51]
Sung MK, Kendall CWC, Koo MM, Rao AV* (1995) Effect of soybean saponin and gypsophilia saponin on growth and viability of colon carcinoma cell in culture. Nutrition and Cancer 23:259-270. [2009 IF=1.98]
Rao AV, Shiwnarain N, Koo M, Jenkins DJA* (1994) Effect of insoluble and soluble fibers on colonic microflora composition in human subjects. Nutrition Research 14:523-535. [2009 IF=1.20]
Fernandes J, Wolever TMS, Rao AV, Morali G, Blendis LM, Koo M, Jenkins DJA* (1994) Effect of lactulose on acetate metabolism in liver cirrhosis. Clinical and Investigative Medicine 17:218-225. [2009 IF=1.15]
Rao AV*, Koo M (1992) Effect of oral administration of bifidobacteria and Neosugar on plasma ammonia concentration in CF1 mice. International Journal of Food Sciences and Nutrition 43:9-17. [2009 IF=1.31]
Kendall CW, Koo M, Sokoloff E, Rao AV* (1992) Effect of dietary oxidized cholesterol on azoxymethane-induced colonic preneoplasia in mice. Cancer Letter 66:241-248. [2009 IF=3.74]
Koo M, Rao AV* (1991) Long-term effect of bifidobacteria on precursor lesions of colonic cancer in CF1 mice. Nutrition and Cancer 16:249-257. [2009 IF=1.98]