Faculty Member

Matthew Kowgier

Email Address(es)
mkowgier@uhnres.utoronto.ca, matthew.kowgier@uhnresearch.ca
Office Phone
416-603-5800 Ext. 2468
Office Address
,
Division(s)/Office
Biostatistics Division
Position
Assistant Professor
SGS Status
Associate Member
Appointment Status
Status Only

Research Interests

  • Data mining and predictive modelling.
  • Statistical methods in genetics.
  • Statistical methods for detecting DNA copy number variants.
  • Collaborative research in pulmonary genetics and sleep apnea genetic epidemiology.

Education & Training History

Ph.D. in Biostatistics, University of Toronto, 2011.

  • Dissertation: Bayesian hidden Markov models for finding DNA copy number changes from SNP genotyping arrays.

M.Sc. in Biostatistics, University of Toronto, 2005.

B.A. in Statistics, York University, 2004.

Other Affiliations

University Health Network

Primary Teaching Responsibilities

  • Introduction to Biostatistics I & II
  • Simulation methods
  • Categorical Data Analysis

Honours & Awards

  • Abstract Scholarship Award, American Thoracic Society, 2013
  • NSERC Canada Graduate Scholarship PGS D2, 2007-2010
  • George and Frances Denzel Award (for excellence in statistics), York University , 2004

Representative Publications

Tang W*, Kowgier M*, Loth DW, Soler Artigas M, Joubert BR, Hodge E, Gharib SA, Smith AV, Ruczinski I, Gudnason V, Mathias RA, Harris TB, Hansel NN, Launer LJ, Barnes KC, Hansen JG, Albrecht E, Aldrich MC, Allerhand M, Barr RG, Brusselle GG, Couper DJ, Curjuric I, Davies G, Deary IJ, Dupuis J, Fall T, Foy M, Franceschini N, Gao W, Gläser S, Gu X, Hancock DB, Heinrich J, Hofman A, Imboden M, Ingelsson E, James A, Karrasch S, Koch B, Kritchevsky SB, Kumar A, Lahousse L, Li G, Lind L, Lindgren C, Liu Y, Lohman K, Lumley T, McArdle WL, Meibohm B, Morris AP, Morrison AC, Musk B, North KE, Palmer LJ, Probst-Hensch NM, Psaty BM, Rivadeneira F, Rotter JI, Schulz H, Smith LJ, Sood A, Starr JM, Strachan DP, Teumer A, Uitterlinden AG, Völzke H, Voorman A, Wain LV, Wells MT, Wilk JB, Williams OD, Heckbert SR, Stricker BH, London SJ, Fornage M, Tobin MD, O Connor GT, Hall IP, Cassano PA (2014), Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function. PLOS One, 9(7):e100776.

Lim AS, Yu L, Kowgier M, Schneider JA, Buchman AS, Bennett DA (2013), Modification of the Relationship of the Apolipoprotein E4 allele to the risk of Alzheimer Disease and Neurofibrillary Tangle Density by Sleep. JAMA Neurology.

Lim AS, Kowgier M, Yu L, Buchman AS, Bennett DA (2013), Sleep fragmentation and the risk of incident Alzeheimer’s Disease and Cognitive Decline in Older Persons. Sleep, 36(7):1027-1032.

Rietveld CA et al. (2013), GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science, 340(6139):1467-1471.

Cousminer DL et al. (2013), Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. Human Molecular Genetics, 22(13):2735-2745.

Parmara PG, Marsha JA, Taala RH, Kowgier M, Uitterlinden AG, Rivadeneira F, Briollais L, Newnham JP, Hofman A, Lye SJ, Steegers EAP, van Duijn CM, Palmer LF, Jaddoe VWV, and Pennel CE (2013) Polymorphisms in genes within the IGF-axis influence antenatal and postnatal growth. Journal of Developmental Origins of Health and Disease, 4(2):157-169.

Patel SR, Goodloe R, De G, Kowgier M, Weng J, Buxbaum SG, Cade B, Fulop T, Gharib SA, Gottlieb DJ, Hillman D, Larkin EK, Lauderdale DS, Li L, Mukherjee S, Palmer L, Zee P, Zhu X, Redline S (2012), Association of genetic loci with sleep apnea in European Americans and African-Americans: the Candidate Gene Association Resource (CARe). PLoS One, 7(11):e48836.