Skip to content

Faculty Member

Andy Kin On Wong PhD

Email Address(es)
Office Phone
416-340-4800 Extension 6276
Office Address
Toronto General Hospital 200 Elizabeth St, 7EN-238 Toronto, ON M5G 2C4
Assistant Scientist UHN, Assistant Clinical Professor McMaster (Adjunct)
Epidemiology Division
Other Initiatives
Assistant Professor
SGS Status
Full Member
Appointment Status
Status Only
Currently Accepting Doctoral Students?

Research Interests

  1. Understanding the disease process for specific knee osteoarthritis phenotypes: a) in those with knee osteoarthritis and altered bone quality or bone turnover; and b) in those with metabolism-related knee osteoarthritis
  2. Exploring treatment of knee osteoarthritis in those with impaired bone quality using antiresorptive therapies
  3. Determining imaging-based predictors of success in knee arthroscopic surgeries
  4. Innovating novel imaging techniques to discover more pain-sensitive measures
  5. Generating population-based references to enable individual-based diagnostic evaluation for MSK diseases
  6. Developing data-driven approaches to image segmentation using pixel morphometry

Background and Experience

I am a data scientist, imaging scientist and epidemiologist. Using this unique combination of skills, I study bones, muscles, joints, and fat in the aging population with particular focus on osteoarthritis, osteoporosis and the interaction of these diseases.

I have trained in conducting primary and secondary epidemiological studies over the last 10 years. As the co-director of the Canadian Multi-Centre Osteoporosis Bone Quality Study (CaMos BQS), a primary research study initiated in 2011, I am studying over 800 women and how peripheral CT-derived structural features can predict incident fractures over 5 years.

I am also involved with leading study and questionnaire design for cycles 5/6 and 7/8 of the Canadian Health Measures Survey – with focus on bone and muscle themes, respectively. This Statistics Canada – Health Statistics Division-led study involves over 10,000 Canadians from coast-to-coast.

In addition, I collaborate on a number of other multi-centre studies including the Study of Osteoporotic Fractures (SOF) in Women, the Osteoporotic Fractures in Men Study (MrOS), and the Osteoarthritis Initiative (OAI) led by colleagues at UCSF.

I am specialized in diagnostic methods and longitudinal studies – in particular, bio/imaging marker tool development, reliability assessment, and disease risk prediction. My research studies cover a broad range of statistical methods including multivariable linear modeling, competing risk/survival analyses, conditional process modeling (moderation), causal inference (mediation), factor analyses, structural equation modeling, and machine learning (variable selection, decision tree, neural networks).

My work involves a combination of data programming in SAS and R, and image processing and analysis in Python.

I am currently seeking new students and volunteers with interest in musculoskeletal health and analytical skills development. Those with a passion for programming are highly encouraged to inquire.

Two unique Joint PhD positions (Conferred by U of T and University of Melbourne) are also available. For more information, please see:

Additional Appointments:

  • Assistant Clinical Professor (Adjunct), Department of Medicine, McMaster University


J Am Med Dir Assoc. 2017 May 01;18(5):414-419
Li G, Papaioannou A, Thabane L, Levine MAH, Ioannidis G, Wong AKO, Lau A, Adachi JD

J Clin Densitom. 2017 Apr – Jun;20(2):226-232
Erlandson MC, Wong AKO, Szabo E, Vilayphiou N, Zulliger MA, Adachi JD, Cheung AM

J Musculoskelet Neuronal Interact. 2014 Dec;14(4):401-10
Wong AK, Beattie KA, Min KK, Gordon C, Pickard L, Papaioannou A, Adachi JD, Canadian Multicentre Osteoporosis Study (CaMos) Research Group

J Musculoskelet Neuronal Interact. 2014 Sep;14(3):246-54
Wong AK, Cawthon PM, Peters KW, Cummings SR, Gordon CL, Sheu Y, Ensrud K, Petit M, Zmuda JM, Orwoll E, Cauley J, Osteoporotic Fractures in Men (MrOS) Research Group

J Clin Densitom. 2015 Jul-Sep;18(3):408-18
Wong AK, Beattie KA, Min KK, Merali Z, Webber CE, Gordon CL, Papaioannou A, Cheung AM, Adachi JD

J Clin Densitom. 2015 Apr-Jun;18(2):260-9
Wong AK, Beattie KA, Min KK, Merali Z, Webber CE, Gordon CL, Papaioannou A, Cheung AM, Adachi JD

J Clin Densitom. 2015 Jan-Mar;18(1):124-35
Wong AK, Beattie KA, Min KK, Webber CE, Gordon CL, Papaioannou A, Cheung AM, Adachi JD

J Clin Densitom. 2015 Jan-Mar;18(1):93-101
Wong AK, Hummel K, Moore C, Beattie KA, Shaker S, Craven BC, Adachi JD, Papaioannou A, Giangregorio L

Osteoarthritis Cartilage. 2009 Nov;17(11):1453-60
Wong AK, Beattie KA, Emond PD, Inglis D, Duryea J, Doan A, Ioannidis G, Webber CE, O’Neill J, de Beer J, Adachi JD, Papaioannou A

Osteoarthritis Cartilage. 2009 May;17(5):579-85
Wong AK, Inglis D, Beattie KA, Doan A, Ioannidis G, Obeid J, Adachi JD, Papaioannou A